Assessing cognitive flexibility in mice using a custom-built touchscreen chamber.

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Tác giả: Ali Goldani, Jayden Hutchison, Mostafa Khavaninzadeh, Amirhossein Mazrouei, Majid H Mohajerani, Leonardo A Molina, Rui C Pais, Robert J Sutherland

Ngôn ngữ: eng

Ký hiệu phân loại: 686.224 Typefaces

Thông tin xuất bản: Switzerland : Frontiers in behavioral neuroscience , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 682437

Automated touchscreen systems have become increasingly prevalent in rodent model screening. This technology has significantly enhanced cognitive and behavioral assessments in mice and has bridged the translational gap between basic research using rodent models and human clinical research. Our study introduces a custom-built touchscreen operant conditioning chamber powered by a Raspberry Pi and a commercially available computer tablet, which effectively addresses the significant cost barriers traditionally associated with this technology. In order to test our prototype, we decided to train C57BL/6 mice on a visual discrimination serial-reversal task, and both C57BL/6 and App
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