Intersecting impact of CAG repeat and Huntingtin knockout in stem cell-derived cortical neurons.

• Tác giả: Naufa Armani, Mariya Barch, Erse Duderstadt, Lindsay Easter, Zohreh Faghihmonzavi, Dan P Felsenfeld, Steve Finkbeiner, Mikelle Foster, Ernest Fraenkel, Terry Huang, Heather Johnson, Julia A Kaye, Stephanie Lam, Matthew J Leventhal, Ricardo Miramontes, Chris Paiz, Yogi Raghav, Kanchan Sarda, Min-Gyoung Shin, Charlene Smith, Jennifer T Stocksdale, Niveda Sundararaman, Leslie M Thompson, Reuben Tomas, Vineet Vaibhav, Jennifer Van Eyk, Thomas F Vogt, Keona Q Wang, Yang Oliver Wang, Jie Wu, Yu-Xin Xu
• Ngôn ngữ: eng
• Thông tin xuất bản: United States : bioRxiv : the preprint server for biology , 2025
• Bộ sưu tập: NCBI
• ID: 682582

Tóm tắt

Huntington's Disease (HD) is caused by a CAG repeat expansion in the gene encoding Huntingtin (HTT