A Versatile Fabrication Route for Screening of Block Copolymer Membranes in Bioprocessing.

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Tác giả: Alberto Alvarez-Fernandez, Daniel G Bracewell, Stefan Guldin, Ke Meng

Ngôn ngữ: eng

Ký hiệu phân loại: 571.64 Membranes

Thông tin xuất bản: United States : ACS omega , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 682932

Traditional poly(ether sulfone) (PES) filters, widely used for sterile, viral, and ultrafiltration, often exhibit restrictions in their selectivity-permeability profile due to their heterogeneous pore size distribution. This limitation has sparked interest in developing novel isoporous membrane materials and fabrication techniques. Among promising candidates, block copolymer (BCP) membranes produced via self-assembly and nonsolvent-induced phase separation (SNIPS) offer significant advantages, including tunable pore size, narrow pore size distribution, high porosity, and enhanced mechanical flexibility. However, optimizing the structure formation in SNIPS remains a complex and time-consuming process, making it unsuitable for rapidly screening new BCP candidates. In response, this study introduces an alternative fabrication approach based on the direct spin-coating of BCPs onto anodic aluminum oxide (AAO) supports. Using this method, a poly(styrene)-
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