Site-Selective Approaches to Attain Fluorescent Human Insulin Conjugates: Balancing the Site of Labeling and the

• Tác giả: Duaa Abuarqoub, Ghayda' AlDabet, Khaled Al-Khatib, Bayan Alkhawaja, Nour Alkhawaja, Bayan Y Ghanim, Andreas Michael, Marwa Mohammad, Nidal A Qinna, Shaun Reeksting, Andrew G Watts
• Ngôn ngữ: eng
• Ký hiệu phân loại: 617.057 Endoscopic surgery
• Thông tin xuất bản: United States : ACS omega , 2025
• Bộ sưu tập: NCBI
• ID: 682943

Tóm tắt

Fluorescent insulin is commonly used for a range of detection and imaging purposes. Achieving site-selective insulin labeling affords superior labeling yield while retaining its biological activity. Insulin labeling is usually achieved using commercial kits with minimal emphasis on the site and degree of labeling. To bridge this gap, this work highlights the essential parameters concerning the development of fluorescent insulin and reflects them on the biological activity of insulin