Gallbladder hemorrhage is a rare medical emergency, often seen in patients with liver or kidney disease, or cancer. Failure to diagnose and treat it early can lead to shock and death. In this article, we present the case of a 64-year-old woman who presented to the emergency room with unstable vital signs and low blood pressure. Physical assessment found epigastric pain and nausea, but no systemic disease. Ultrasound diagnosed a suspected gallbladder hemorrhage, and she underwent immediate resuscitation and emergency computed tomography (CT). She was consulted with general surgery for gallbladder removal and discharged five days later. Interestingly, six months later, she experienced back pain and discomfort. MRI revealed a suspected bone metastasis, and she was eventually diagnosed with stage IVB lung cancer (T4N3M1c).