Chemical constituents from the stems of Ephedra intermedia and their α-glucosidase and AChE inhibitory effects.

• Tác giả: Yan-Gang Cao, Xu Chen, Wei-Sheng Feng, Yan-Ling Liu, Di Lu, Ying Niu, Bing-Xian Zhao, Yi-Xin Zhao, Xiao-Ke Zheng
• Ngôn ngữ: eng
• Ký hiệu phân loại: 271.6 *Passionists and Redemptorists
• Thông tin xuất bản: Netherlands : Fitoterapia , 2025
• Bộ sưu tập: NCBI
• ID: 68389

Tóm tắt

Five undescribed glycosides (1-5) and eight known compounds (6-13) were isolated from the stems of Ephedra intermedia. Their chemical structures were determined by analysis of NMR, ECD, and MS data. In addition, The in vitro bioactive assay, α-glucosidase and acetylcholinesterase (AChE) inhibitory activities, suggested that compounds 11 and 12 exhibited obvious inhibitory effects on α-glucosidase with the IC