Bowen's disease is a non-melanocytic in situ squamous cell carcinoma of the epidermis. Having a multifactorial etiology, its incidence has been found to be the highest in Caucasians. It commonly occurs as a solitary lesion in the elderly on the photoexposed areas of the skin, mainly in the head and neck region. We present a case of a single, pruritic, oozy ulcerated lesion in the left upper labia majora in a 32-year-old female for the last six months who had undergone various treatments before presenting to our institute. Excision followed by histopathological examination led to the diagnosis of Bowen's disease. Our case focuses on the potential of Bowen's disease to mimic common dermatological lesions, and therefore a high degree of suspicion assisted by histopathological examination is essential for early and rapid diagnosis, along with a multimodality approach to management.