STATEMENT OF PROBLEM: The high recurrence rate of denture stomatitis may be related to the strong resistance of fungi. Therefore, the method of providing biomaterials with antifungal properties is an attractive solution for improving microbial control. PURPOSE: Against the drug resistance of Candida albicans, this study aim to elucidate the photocatalytic antibacterial effect of TiO METHODS: In this study, TiO RESULTS: TiO CONCLUSION: Therefore, it is inferred that the optimal photocatalytic antimicrobial and mechanical properties of PMMA materials are achieved by adding 1%wt TiO