Limitations and enhancement opportunities for variceal rebleeding prediction model in patients with cirrhosis.

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Tác giả: Guang-Bin Chen, Long-Jiang Chen, Rong-Mei Tang, Fei Wu

Ngôn ngữ: eng

Ký hiệu phân loại: 519.287 Expectation and prediction

Thông tin xuất bản: United States : World journal of gastroenterology , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 684139

A multicenter study recently published introduced a novel prognostic model for predicting esophagogastric variceal rebleeding after endoscopic treatment in patients with cirrhosis. The model incorporated six readily available clinical variables-albumin level, aspartate aminotransferase level, white blood cell count, ascites, portal vein thrombosis, and bleeding signs-and demonstrated promising predictive performance. However, limitations, including the retrospective design and exclusion of patients with hepatocellular carcinoma, may affect the generalizability of the model. Additionally, further improvement is needed in the model's discrimination between intermediate- and high-risk groups in external. Prospective validation and inclusion of additional variables are recommended to enhance predictive accuracy across diverse clinical scenarios.
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