Isolated Testicular Metastasis From Prostate Cancer: A Rare Presentation 15 Years Posttreatment.

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Tác giả: Asadullah Aslam, Syed Jaffry, Syed Yousaf Khalid, Claudio Lizarralde, Tauqir Aslam Waraich

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: United States : Cureus , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 684155

Testicular metastases from prostate cancer (PCa) are exceedingly rare and are typically accompanied by other metastatic sites. We present the case of an 82-year-old male patient who developed isolated testicular metastasis 15 years after undergoing radiotherapy and androgen deprivation therapy (ADT) for localized PCa. The patient presented with a palpable left testicular mass, which was confirmed to be a metastatic prostate adenocarcinoma by histopathological and immunohistochemical analyses. Orchiectomy was performed for both diagnostic and therapeutic purposes, resulting in a significant decline in serum PSA levels. The patient continued ADT with regular monitoring, and no further metastases were detected. This case highlights the importance of long-term surveillance and advanced diagnostic techniques for detecting the rare metastatic presentations of PCa. Although isolated testicular metastases may have a better prognosis than other metastatic patterns, optimal postorchiectomy management remains uncertain, underscoring the need for further research and a multidisciplinary approach.
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