A mechanistic basis for genetic assimilation in natural fly populations.

• Tác giả: Giacomo Cavalli, Marta Coronado-Zamora, Maximilian H Fitz-James, Josefa González, Giorgio L Papadopoulos, Gonzalo Sabarís, Bernd Schuettengruber
• Ngôn ngữ: eng
• Thông tin xuất bản: United States : Proceedings of the National Academy of Sciences of the United States of America , 2025
• Bộ sưu tập: NCBI
• ID: 685177

Tóm tắt

Genetic assimilation is a process by which a trait originally driven by the environment becomes independent of the initial cue and is expressed constitutively in a population. More than seven decades have passed since Waddington's pioneering demonstration of the acquisition of morphological traits through genetic assimilation, but the underlying mechanism remains unknown. Here, we address this gap by performing combined genomic analyses of Waddington's genetic assimilation experiments using the ectopic veins (EV) phenocopy in