Discovery of pea protein-derived DPP-IV inhibitory peptides: Transport across Caco-2 cell monolayers and molecular mechanisms.

• Tác giả: Chang Chang, Zhengqiang Jiang, Jia Lei, Qiaojuan Yan, Mengyao Zhao
• Ngôn ngữ: eng
• Ký hiệu phân loại: 959.3034 *Thailand
• Thông tin xuất bản: Netherlands : International journal of biological macromolecules , 2025
• Bộ sưu tập: NCBI
• ID: 685298

Tóm tắt

Dipeptidyl peptidase IV (DPP-IV) inhibitory peptides derived from food proteins have been studied to regulate hyperglycemia, but their effects on transepithelial transport and inhibitory mechanisms remain unclear. In this study, pea protein was ultrasonicated then dually hydrolyzed by Pseudomonas aeruginosa protease (PaproA) and acid protease to exhibit great DPP-IV inhibitory activity (IC