Combined effects of time-restricted eating and exercise on short-term blood glucose management in individuals with Type 2 Diabetes Mellitus: The TREx study, a randomised controlled trial.

• Tác giả: Bronte Arthur, Ana Paula Bravo-Garcia, Sophie C Broome, Brooke L Devlin, Rebecca C Hall, Shona L Halson, John A Hawley, Kristel Janssens, Rich D Johnston, Evelyn B Parr, Bridget E Radford, Nicolin Tee
• Ngôn ngữ: eng
• Ký hiệu phân loại: 620.106 Applied fluid mechanics
• Thông tin xuất bản: Ireland : Diabetes research and clinical practice , 2025
• Bộ sưu tập: NCBI
• ID: 685384

Tóm tắt

 AIMS: Time-restricted eating (TRE) is a chrono-nutrition strategy where the daily 'eating window' is reduced to 8-10 h. We investigated the acute (14-h) effects of TRE, with and without post-meal exercise, on blood glucose and insulin concentrations in people with type 2 diabetes mellitus. METHODS: Fourteen participants (5 F, 9 M
  HbA1c: 7.6 ± 1.0%) completed four conditions in this randomised crossover study: CON (eating window, 0800-2000 h), CON with exercise (CON + Ex
  0800-2000 h + 15 min walking at 60% VO RESULTS: Reducing the eating window had little effect on plasma glucose 14-h area under the curve (AUC). Exercise reduced insulin 14-h AUC (P=0.01) with no additive effect of TRE. CONCLUSION: Post-meal exercise lowered 14-h insulin AUC, neither 8-h TRE nor post-meal exercise altered 14-h blood glucose compared with 12-h eating window. Future work should focus on long-term effects of TRE combined with exercise for enhancing blood glucose in people with type 2 diabetes mellitus.