Bioprocess biomarker identification and diagnosis for industrial mAb production based on metabolic profiling and multivariate data analysis.

• Tác giả: Yuting Lu, Jianyang Pan, Haibin Qu, Yingting Shi, Yuxiang Wan, Haibin Wang, Xinyuan Xie, Jiayu Yang
• Ngôn ngữ: eng
• Ký hiệu phân loại: 611.01816 Human anatomy, cytology, histology
• Thông tin xuất bản: Germany : Bioprocess and biosystems engineering , 2025
• Bộ sưu tập: NCBI
• ID: 685727

Tóm tắt

Monoclonal antibody (mAb) production is a complex bioprocess influenced by various cellular and metabolic factors. Understanding these interactions is critical for optimizing manufacturing and improving yields. In this study, we proposed a diagnostic and identification strategy using quantitative proton nuclear magnetic resonance (