Pulmonary manifestations and clinical management of echinococcosis in a low-endemic region of Mexico: a 15-year retrospective cohort study at a tertiary hospital.

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Tác giả: Víctor Hugo Ahumada Topete, Arnoldo Aquino Gálvez, Manuel Castillejos Lopez, José Alberto Choreño Parra, Rosario Fernandez Plata, Misael Osmar Garcia Martin, Graciela Hernandez Silva, Anjarath Higuera Iglesias, Jolenny Jimenez Lopez, David Martinez Briseño, Alicia Jackeline Parra Vargas, Francisco Bernardo Perez Orozco, Elio Germán Recinos Carrera, Karina Danae Sevilla Gutiérrez, Luz María Torres Espindola, Marco Villanueva Reza, Joaquín Zúñiga Ramos

Ngôn ngữ: eng

Ký hiệu phân loại: 025.3173 Bibliographic analysis and control

Thông tin xuất bản: Japan : Tropical medicine and health , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 686457

 BACKGROUND: Cystic echinococcosis has a low incidence even in endemic countries. It is a chronic and complex zoonosis that in many cases presents delay in diagnosis
  it typically affects the liver in up to 90% of the cases, being disseminated pulmonary disease the most common in young subjects, while the rate of cases located only in the pulmonary parenchyma is low. In Mexico it is considered a disease of low endemicity. MATERIAL AND METHODS: We retrospectively collected data from patients with suspected echinococcosis infection from the hospital discharge database. RESULTS: Of the 70 patients in the database, 59 had a clinical history (84.3%), of whom 11 had a histopathological diagnosis of cystic echinococcosis and were included in this study, 67.6% were female, with a median age of 32 years (IQR 17-53.5). A total of 45.6% had some comorbidity, the most frequent being type II diabetes mellitus (80%)
  only 54.6% had lived in a rural area as a risk factor, while only 27.2% had exposure to canines. All cases were symptomatic, with a mean symptom duration of 49 days. A total of 81.8% had exclusive pulmonary disease, while the rest had simultaneous lung and liver involvement. No case presented spontaneous rupture. All cases received anthelmintic treatment and, in 9 cases, surgical resection of the pulmonary parenchyma. The only postsurgical complication was a chylothorax with adequate resolution. The median follow-up in months was 8.3 (IQR 3.7 to 10.7 months), and almost two-thirds of the cases presented dyspnea grade 2-3 (mMRC) as sequelae. CONCLUSION: Of all the patients studied with pulmonary echinococcosis, only two presented with hepatic-pulmonary hydatid disease, and spontaneous cyst rupture was not reported. About half had exposure to cattle as a risk factor, while no specific risk factor was identified in the rest of the subjects.
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