A Novel Derivatization-Free Approach for Analysis of (+)2-Aminobutanol and Ethambutol Hydrochloride in Tablets Preparation Using RP-HPLC-NQAD.

• Tác giả: Liya Hong, Chao Liu, Ying Luo, Hao Ruan, Yunfeng Shi, Weike Su, Qian Yang, Minglong Ye
• Ngôn ngữ: eng
• Ký hiệu phân loại: 615.43 Pills, capsules, tablets, troches, powders
• Thông tin xuất bản: England : Biomedical chromatography : BMC , 2025
• Bộ sưu tập: NCBI
• ID: 686538

Tóm tắt

A novel and rapid RP-HPLC coupled with nano quantity analyte detector (NQAD) method was developed for determination of ethambutol hydrochloride and (+)2-aminobutanol in drug products. NQAD is an aerosol-based detector that can be used for the direct detection of the substance lacking ultraviolet chromophores. The two highly polar analytes were separated on a C