Exploring the scope of inspiratory muscle training in difficult weaning: reflections on the multicentre RCT.

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Tác giả: Sireesha Chilakapati, Bharat Paliwal, Jyothi Koteswara Rao

Ngôn ngữ: eng

Ký hiệu phân loại: 355.007155 Military science

Thông tin xuất bản: England : Journal of intensive care , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 686756

We commend the authors for their insightful study on inspiratory muscle training (IMT) in mechanically ventilated patients with difficult weaning, highlighting the robust use of maximum inspiratory pressure (MIP) as a key outcome. We suggest that a lower baseline maximum inspiratory pressure cutoff could better target patients with significant inspiratory dysfunction, improving the study's precision. Additionally, alternative imputation techniques, such as multiple imputation, could strengthen the handling of missing data. While the sample size calculation was appropriate, the unbalanced group sizes raise concerns about generalisability. Future research could benefit from subgroup analyses, individual response curves, and further investigation into the unexpected adverse effects observed in the low-intensity group to refine the inspiratory muscle training protocols.
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