Gold nanorods as multidimensional optical nanomaterials: machine learning-enhanced quantitative fingerprinting of proteins for diagnostic applications.

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Tác giả: Samira Abbasi-Moayed, Mahmood Akbari, Mahdi Ghamsari, Mohammad Reza Hormozi-Nezhad, Malik Maaza, Afsaneh Orouji

Ngôn ngữ: eng

Ký hiệu phân loại: 912.01 Philosophy and theory

Thông tin xuất bản: England : Nanoscale , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 686958

The rapid and precise quantification and identification of proteins as key diagnostic biomarkers hold significant promise in allergy testing, disease diagnosis, clinical treatment, and proteomics. This is crucial because alterations in disease-associated genetic information during pathogenesis often result in changes in protein types and levels. Therefore, the design of portable, fast, user-friendly, and affordable sensing platforms rather than a single-sensor-per-analyte strategy for multiplex protein detection is quite consequential. In the present research, a robust multicolorimetric probe based on the inhibited etching of gold nanorods (AuNRs) allowing unambiguous high-performance visual and spectral quantification and identification of proteins in human urine samples was designed. Most recently, we discovered that
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