METHODS: Strains isolated from KT patients were collected, and antimicrobial susceptibility analysis was verified RESULTS: A total of 43 KP isolates were collected from KT patients in this study, and 24 of them were identified as CRKP (55.81%). KPC-2 genes were detected in all of the CRKP strains (100%), and other carbapenemase genes were not detected. Twenty-two strains (91.67%) of CRKP strains were identified as ST11, while 2 (8.33%) were ST15-typing. Finally, two highly virulent CONCLUSION: The resistance rate to carbapenem of KP from KT patients exceeded the regional average with predominant ST typing of ST11. Clinical data were analyzed to derive some high-risk factors for CRKP infection. Therefore, we recommend early prophylactic isolation of transplant patients with high-risk factors for CRKP infection to improve the quality of nosocomial control.