In Silico and In Vivo Evaluation of Novel 2-Aminobenzothiazole Derivative Compounds as Antidiabetic Agents.

• Tác giả: Juan Andres Alvarado Salazar, Alejandro Cruz, Jessica Elena Mendieta Wejebe, Brenda Moreno de Jesús, Ivonne María Olivares Corichi, David Patiño González, Feliciano Tamay Cach, Miguel Valdes
• Ngôn ngữ: eng
• Ký hiệu phân loại: 912.01 Philosophy and theory
• Thông tin xuất bản: Switzerland : International journal of molecular sciences , 2025
• Bộ sưu tập: NCBI
• ID: 68735

Tóm tắt

 Currently, there are several drugs used for the treatment of type 2 diabetes (T2D)
  however, all of them have adverse effects. Benzothiazoles have a broad spectrum of biological activities such as antidiabetic. This study aimed to evaluate in silico and in vivo two series of 2-aminobenzothiazole derivatives linked to isothioureas (