Intestinal polyps have been described in association with chronic schistosomiasis, and must be differentiated from malignant tumors and appropriately managed. This uncommon condition may be very rarely detected in people from non-endemic areas of this zoonosis, who were occasionally infected during some travel period. The lesions are more frequently described in men, and predominating in the colon. The diagnosis is confirmed by histopathological evaluations and finding eggs of Schistosoma in biopsy samples. The use of Praziquantel has been a very effective treatment. The authors emphasize the diagnosis confirmation as early as possible, avoiding mistakes with cancer.