Differential T follicular helper cell phenotypes distinguish IgE-mediated milk allergy from eosinophilic esophagitis in children.

• Tác giả: Keith Benkov, M Cecilia Berin, Xin Chen, Maria Curotto de Lafaille, David Dunkin, Weslley Fernandes-Braga, Wajiha Kazmi, Joanne Lai, Daniel Lozano-Ojalvo, David Menchén-Martínez, Leticia Pérez-Rodríguez, Nanci Pittman, Hugh A Sampson, Scott Tyler
• Ngôn ngữ: eng
• Ký hiệu phân loại: 668.4237 Plastics
• Thông tin xuất bản: United States : The Journal of allergy and clinical immunology , 2025
• Bộ sưu tập: NCBI
• ID: 688485

Tóm tắt

BACKGROUND: IgE-mediated food allergy and eosinophilic esophagitis (EoE) are diseases commonly triggered by milk. Milk-responsive CD4 OBJECTIVE: We sought to identify differences in CD4 METHOD: The total and milk-specific CD4 RESULTS: Circulating milk-responsive T cells could be identified in active EoE and MA. An increased frequency of T CONCLUSIONS: Our studies demonstrate a dichotomy of T