Molecular Insights Into β-Glucuronidase Inhibition by Alhagi Graecorum Flavonoids: A Computational and Experimental Approach.

• Tác giả: Esam M Al-Shaebi, Emadeldin M Kamel, Saleh Maodaa, Al Mokhtar Lamsabhi
• Ngôn ngữ: eng
• Thông tin xuất bản: Germany : ChemistryOpen , 2025
• Bộ sưu tập: NCBI
• ID: 688871

Tóm tắt

In this study, we aimed to investigate the inhibitory mechanisms of β-glucuronidase by flavonoids derived from Alhagi graecorum through both experimental and computational approaches. The activity of β-glucuronidase was assessed using an in vitro enzyme inhibition assay, where myricetin and chrysoeriol were identified as potent inhibitors based on their low IC