Spiral cardiac quantitative susceptibility mapping for differential cardiac chamber oxygenation-Initial validation in relation to invasive blood sampling.

• Tác giả: Caitlin Chiu, Jiwon Kim, Chao Li, Jiahao Li, Nupoor Narula, Thanh D Nguyen, Mahniz Reza, Pascal Spincemaille, Pablo Villar-Calle, Yi Wang, Jonathan W Weinsaft, Jinwei Zhang, Robert S Zhang
• Ngôn ngữ: eng
• Thông tin xuất bản: United States : Magnetic resonance in medicine , 2025
• Bộ sưu tập: NCBI
• ID: 688948

Tóm tắt

PURPOSE: To develop a breath-hold cardiac quantitative susceptibility mapping (QSM) sequence for noninvasive measurement of differential cardiac chamber blood oxygen saturation (ΔSO METHODS: A non-gated three-dimensional stack-of-spirals QSM sequence was implemented to continuously sample the data throughout the cardiac cycle. Measurements of ΔSO RESULTS: Compared with navigator QSM (average acquisition time 419 ± 158 s), spiral QSM reduced the scan time on average by over 20-fold to a 20-s breath-hold. In all three cohorts, spiral QSM and navigator QSM yielded similar ΔSO CONCLUSION: Breath-hold three-dimensional spiral cardiac QSM for measuring differential cardiac chamber blood oxygenation is feasible and provides values in good agreement with navigator cardiac QSM and with reference right heart catheterization.