Upon injury, both mammalian and plant cells activate a survival mechanism by sensing endogenous damage-associated molecular patterns (DAMPs). Plant elicitor peptides (Peps), a representative DAMP, are released from their precursors (PROPEPs
Precursors of Peps) through cleavage by metacaspases (MCs), but the control of Pep generation remains unclear. Here, we discovered that several PROPEPs in Arabidopsis thaliana are substrates for SUMOylation and that Ca