Isolation, structural characterization, and molecular docking studies on the bioactive compound from n-Hexane extract of

• Tác giả: Rathi Muthaiyan Ahalliya, Prabhu Damodharan, Dhivya Devaraj, Chella Perumal Palanisamy, Pratibha Prabhakaran, Abirami Shanmugam, Harshini Swaminathan, Gopalakrishnan Velliyur Kanniappan
• Ngôn ngữ: eng
• Ký hiệu phân loại: 553.3 Iron
• Thông tin xuất bản: Germany : Journal of complementary & integrative medicine , 2025
• Bộ sưu tập: NCBI
• ID: 689246
• Chủ đề: 1. Isolation; 2. Structural; 3. Characterization

Tóm tắt

OBJECTIVES: Natural flora historically has played a substantial part in drug development since they serve as active ingredients in medications and templates for the synthesis of novel pharmaceuticals. METHODS: n-Hexane extract using chromatographic techniques and structurally characterize them using spectroscopic techniques. Further, RESULTS: A mixture of stigmasterol with straight-chain monounsaturated alcohol (C CONCLUSIONS: Based on the outcomes, it can be concluded that the stigmasterol with straight-chain monounsaturated alcohol may act as a novel inhibitor for Aurora 2 Kinase. In the future, it may lead to the development of drugs targeting Aurora 2 Kinase for the effective treatment of pancreatic cancer.