Role of echocardiographic indicators of right ventricular dysfunction in predicting 30-day mortality in non-high- -risk patients with acute pulmonary embolism in different variants of the Bova score.

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Tác giả: Radosław Borek, Julia Chukwu, Ositadima Chukwu, Michał Medygrał, Marek Rajzer, Anna Skwarek, Katarzyna Stolarz-Skrzypek, Jerzy Wiliński

Ngôn ngữ: eng

Ký hiệu phân loại: 379.28 Place of religion in public schools

Thông tin xuất bản: Poland : Kardiologia polska , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 689288

 BACKGROUND: The Bova score is a validated tool for short-term mortality risk stratification in normotensive patients with acute pulmonary embolism (PE). The prognostic value of echocardiographic parameters in this group of patients remains controversial. AIMS: We aimed to assess the role of echocardiographic indicators of right ventricular dysfunction in different variants of the Bova score. METHODS: Patients with PE confirmed by computed tomography pulmonary angiography had a transthoracic echocardiogram performed during the first day of hospitalization and 30-day follow-up. RESULTS: One hundred eleven consecutive subjects with non-high-risk PE entered the analysis - 55 men (49.6%), at a median age of 69 (58-79) years
  12 patients died during the 30-day follow-up. Among 3 Bova score variants with different echocardiographic criteria used in practice, the original one AD 2014 had the best but, objectively, poor predictive strength - the area under the curve (AUC) of 0.679. The Bova score with the right-to-left ventricle ratio >
 1 and tricuspid annular plane systolic excursion <
 16 mm was an even worse indicator (AUC 0.652), whereas the Bova score with free wall longitudinal strain >
 -19% and Bova 60/60 sign had fair predictability (AUC 0.701 and 0.731, respectively). Still, they were inferior to the simplified Pulmonary Embolism Severity Index (sPESI, AUC - 0.815). The subjects with Bova score variants with points >
 4 had a higher risk of death (hazard risk of 1.43-1.59) and with an sPESI ≥1 point had a hazard risk of 2.02. CONCLUSIONS: Various echocardiographic markers of right ventricular dysfunction within divergent variants of the Bova score yield different prediction strengths but are all inferior to the sPESI score.
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