Noninvasive blood-brain barrier integrity mapping in patients with high-grade glioma and metastasis by multi-echo time-encoded arterial spin labeling.

• Tác giả: Matthias Günther, Gabriel Hoffmann, Kirsten Jung, Stephan Kaczmarz, Amnah Mahroo, Marie-Christin Metz, Christine Preibisch, Lena Václavů, Matthias J P van Osch, Benedikt Wiestler, Claus Zimmer
• Ngôn ngữ: eng
• Ký hiệu phân loại: 612.826 Diencephalon and brain stem
• Thông tin xuất bản: United States : Magnetic resonance in medicine , 2025
• Bộ sưu tập: NCBI
• ID: 689588

Tóm tắt

 PURPOSE: In brain tumors, disruption of the blood-brain barrier (BBB) indicates malignancy. Clinical assessment is qualitative
  quantitative evaluation is feasible using the K METHODS: We acquired 3T MRI data from 28 patients with intraparenchymal brain tumors (World Health Organization Grade 3 & 4 gliomas [n = 17] or metastases [n = 11]) and 17 age-matched healthy controls. The protocol included multi-echo and single-echo Hadamard-encoded arterial spin labeling, dynamic susceptibility contrast, and conventional clinical imaging. T RESULTS: T CONCLUSION: T