Focus on the Forgotten Organelle: Regulation of Lysosomes in Skeletal Muscle.

• Tác giả: Sabrina Champsi, David A Hood, Anastasiya Kuznyetsova, Neushaw Moradi, Victoria C Sanfrancesco
• Ngôn ngữ: eng
• Ký hiệu phân loại: 343.09482 Military, defense, public property, public finance, tax, commerce (trade), industrial law
• Thông tin xuất bản: United States : Exercise and sport sciences reviews , 2025
• Bộ sưu tập: NCBI
• ID: 689668
• Chủ đề: 1. Focus; 2. On; 3. The

Tóm tắt

Research on the role of the lysosome as the terminal organelle in autophagy and in communicating with other organelles in skeletal muscle is in its infancy. We hypothesize that the lysosome can adapt positively to exercise to improve the clearance of cargo, like dysfunctional mitochondria, within muscle, representing an important therapy for protein homeostasis in aging and muscle disuse.