Evaluating the transcriptional regulators of arterial gene expression via a catalogue of characterized arterial enhancers.

• Tác giả: Niharika Adak, Susann Bruche, Sarah De Val, Ian R McCracken, Svanhild Nornes
• Ngôn ngữ: eng
• Ký hiệu phân loại: 004.338 Systems analysis and design, computer architecture, performance evaluation of real-time computers
• Thông tin xuất bản: England : eLife , 2025
• Bộ sưu tập: NCBI
• ID: 689704

Tóm tắt

The establishment and growth of the arterial endothelium require the coordinated expression of numerous genes. However, regulation of this process is not yet fully understood. Here, we combined in silico analysis with transgenic mice and zebrafish models to characterize arterial-specific enhancers associated with eight key arterial identity genes (