AIMS: To discuss the need for nurse researchers to consider to the potential for psychological distress when conducting studies on sensitive topics. DESIGN: Discursive paper. METHODS: Drawing from existing literature, we highlight the ethical obligations of researchers to recognise and manage their emotional responses, especially as these can potentially lead to burnout and re-traumatization. In this paper, we propose practical strategies to mitigate these risks, including trauma-informed practices, peer support systems, structured mentorship and the establishment of vicarious trauma (VT) plans. CONCLUSION: Prioritising researcher well-being in nursing research is essential for ethical practices and the mental health of those involved in undertaking research in sensitive areas. IMPLICATIONS FOR THE PROFESSION AND/OR PATIENT CARE: Support strategies, such as formal team debriefings, resilience training, VT plans and peer support, can foster safer and healthier research environments, when researching in sensitive areas.