Daurisoline Inhibits Progression of Triple-Negative Breast Cancer by Regulating the γ-Secretase/Notch Axis.

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Tác giả: Xiaoyong Chen, Mei Feng, Hui Jia, Kefan Yang, Kuo Yao, Xiangyi Zhan

Ngôn ngữ: eng

Ký hiệu phân loại: 636.0838 Animal husbandry

Thông tin xuất bản: Korea (South) : Biomolecules & therapeutics , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 690662

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Triple-negative breast cancer (TNBC) is a subtype of breast cancer that is challenging to treat and lacks targeted therapeutic drugs in the clinic. Natural active ingredients provide promising opportunities for discovering and developing targeted therapies for TNBC. This study investigated the effects of daurisoline on TNBC and elucidated its potential mechanisms. Using network pharmacology, a correlation was identified between daurisoline, derived from

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