Association between plasma cytokine levels and multiple neuroimaging modalities in mild cognitive impairment.

• Tác giả: Takuya Ataka, Takuya Hanaoka, Noriyuki Kimura, Teruaki Masuda, Etsuro Matsubara, Atsuhito Nakamichi
• Ngôn ngữ: eng
• Ký hiệu phân loại: 599.31 *Edentata (Xenarthra), Pholidota, Tubulidentata
• Thông tin xuất bản: United States : Journal of Alzheimer's disease : JAD , 2025
• Bộ sưu tập: NCBI
• ID: 691218

Tóm tắt

 BackgroundThe relationship between peripheral cytokines and neuroimaging biomarkers for Alzheimer's disease (AD) is not yet well established.ObjectiveTo determine the association of cytokine plasma levels with brain amyloid deposition, cortical glucose metabolism, hippocampal volume, and white matter lesions (WMLs) in older adults with mild cognitive impairment (MCI).MethodsWe recruited 50 older individuals with amnestic MCI (25 men and 25 women
  median age, 75 years) and performed plasma analysis,