Visible-light-mediated radical difunctionalization of alkenes with aromatic aldehydes.

• Tác giả: Jun Du, Tao Geng, Xiaoxiao Hu, Huawen Huang, Lin Liu, Zhiqiang Shi, Zhenhua Xu, Youpeng Zuo
• Ngôn ngữ: eng
• Ký hiệu phân loại: 541.3533 Miscellaneous topics in physical chemistry
• Thông tin xuất bản: England : Organic & biomolecular chemistry , 2025
• Bộ sưu tập: NCBI
• ID: 691259

Tóm tắt

We have developed a visible-light-mediated three-component tandem reaction of aromatic aldehydes with acrylates using a Hantzsch ester as the hydrogen atom transfer reagent, generating diethyl pentanedioate products in a one-pot synthesis. The reaction facilitates direct formation of acyl groups from the corresponding aldehydes, which are subsequently coupled successively to two molecules of acrylate in a Giese addition.