Enhanced combination therapy through tumor microenvironment-activated cellular uptake and ROS-sensitive drug release using a dual-sensitive nanogel.

• Tác giả: Qinfeng Chen, Qinghua Chen, Du Cheng, Chenhui Hao, Haowen Li, Xiaoxia Li, Shuang Liu, ChiYi Ou, Jing Yang, Dongsheng Yu, Jianming Yuan, Mingxiang Zuo
• Ngôn ngữ: eng
• Ký hiệu phân loại: 001.44 Support of and incentives for research
• Thông tin xuất bản: England : Biomaterials science , 2025
• Bộ sưu tập: NCBI
• ID: 691267

Tóm tắt

Although the co-delivery of chemotherapeutic and photodynamic agents has been studied for years, developing a simple and efficient nanoplatform for high co-delivery efficiency remains a challenge for clinical applications. In this study, we prepared a reactive oxygen species (ROS) and pH dual-sensitive nanogel for the co-encapsulation of doxorubicin (DOX) and indocyanine green (ICG)-conjugated bovine serum albumin (BSA)