Transcriptomic landscape of cumulus cells from patients <38 years old with a history of poor ovarian response (POR) treated with platelet-rich plasma (PRP).

• Tác giả: Yigit Cakiroglu, Rolando Garcia-Milian, Nola Herlihy, James Knight, Cheri K Margolis, Andres Reig, Leah M Roberts, Emre Seli, Bulent Tiras, Shiny Titus, Marie D Werner, Christine V Whitehead, Raziye Melike Yildirim
• Ngôn ngữ: eng
• Ký hiệu phân loại: 362.19 Services to patients with specific conditions
• Thông tin xuất bản: United States : Aging , 2025
• Bộ sưu tập: NCBI
• ID: 691502

Tóm tắt

Intraovarian injection of autologous platelet-rich plasma (PRP) has recently been investigated as a potential treatment for patients with diminished ovarian reserve. In the current study, differential gene expression in cumulus cells obtained from patients treated with PRP was compared to controls. RNA sequencing libraries were constructed from the cumulus cells, and differential expression analysis was performed with a false discovery rate threshold of