Cellular uptake mechanisms of a diselenide-based ROS-responsive nanocarrier in oxidatively stressed colon cells.

• Tác giả: Wenli Dai, Jinheng Hao, Dong Li, Wanqi Liang, Qiongqiong Yang, Bo-Bo Zhang
• Ngôn ngữ: eng
• Ký hiệu phân loại: 796.42069 Weight lifting, track and field, gymnastics
• Thông tin xuất bản: England : Chemical communications (Cambridge, England) , 2025
• Bộ sưu tập: NCBI
• ID: 691507

Tóm tắt

Here, we demonstrate that a diselenide-based ROS-responsive nanocarrier exhibits a highly sensitive response to ROS and excellent ROS scavenging activity. Mechanism studies indicate that it can be efficiently taken up by oxidatively stressed colon cells through folate receptor-mediated endocytosis, underscoring its potential for targeted drug delivery in treating colon diseases.