Diketopiperazine and purine alkaloids from the tubers of Pinellia pedatisecta Schott and their protective activities against Aβ

• Tác giả: Yan-Gang Cao, Lan Chen, Xu Chen, Fang-Ge Chi, Wei-Sheng Feng, Feng-Xiao Hao, Yan-Ling Liu, Di Lu, Ying Niu, Bing-Xian Zhao, Xiao-Ke Zheng
• Ngôn ngữ: eng
• Ký hiệu phân loại: 794.10285 Chess
• Thông tin xuất bản: England : Phytochemistry , 2025
• Bộ sưu tập: NCBI
• ID: 691751

Tóm tắt

Nine undescribed diketopiperazine alkaloids (1-8, 28) and three undescribed purine alkaloids [35, (±)-36, (±)-37], along with twenty-six known compounds, were isolated from the tubers of Pinellia pedatisecta Schott. Their structures were determined by analysis of their 1D and 2D NMR spectra, HRESIMS, DP4+, ECD, and optical rotation data. In addition, the protective effects of all compounds against Aβ