Prognostic circulatory signature metabolites of stable versus unstable angina: an application of NMR spectroscopy.

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Tác giả: Ashish Gupta, Aditya Kapoor, Shiridhar Kashyap, Anupam Kumar, Deepak Kumar, Sudeep Kumar, Khushbhu Meena, Ankit Kumar Sahu

Ngôn ngữ: eng

Ký hiệu phân loại: 631.816 Methods of application

Thông tin xuất bản: United States : American journal of physiology. Heart and circulatory physiology , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 691788

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In spite of the ongoing efforts to probe the metabolic signatures of stable (SA) from unstable (UA) angina, it is concerning that to date there are no clinically validated circulatory biochemical signatures against the intrinsic anatomical changes that are screened by invasive coronary angiography. Hence, the aim of this study is to generate precise biochemical fingerprints using filtered serum-based metabolomics and high-throughput nuclear magnetic resonance (NMR) spectroscopy to accurately distinguish the metabolic signatures of patients suffering with SA or UA angina. The study includes 118 filtered serum samples from patients suffering from UA (

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