Multiomics analysis unveils the cellular ecosystem with clinical relevance in aldosterone-producing adenomas with

• Tác giả: Takeshi Bamba, Masatoshi Eto, Masamichi Fujita, Tazuru Fukumoto, Shojiro Haji, Norifusa Iwahashi, Yoshihiro Izumi, Hiroki Kaneko, Namiko Kawamura, Hiroshi Nakao, Kohta Nakatani, Yoshinao Oda, Tatsuki Ogasawara, Seishi Ogawa, Yoshihiro Ogawa, Masahide Seki, Shuichi Shimma, Yutaka Suzuki, Hironobu Umakoshi, Maki Yokomoto-Umakoshi
• Ngôn ngữ: eng
• Ký hiệu phân loại: 021.2 Relationships with the community
• Thông tin xuất bản: United States : Proceedings of the National Academy of Sciences of the United States of America , 2025
• Bộ sưu tập: NCBI
• ID: 692042

Tóm tắt

Aldosterone-producing adenomas (APA), a major endocrine tumor and leading subtype of primary aldosteronism, cause secondary hypertension with high cardiometabolic risks. Despite potentially producing multiple steroid hormones, detailed cellular mechanisms in APA remain insufficiently studied. Our multiomics analysis focusing on APA with