Specific microbial ratio in the gut microbiome is associated with multiple sclerosis.

• Tác giả: Leeann S Aguilar Meza, Catherine Cherwin, Tracey Cho, Sudeep Ghimire, Christine Gill, Jemmie Hoang, Peter C Lehman, Ashutosh K Mangalam, Heena Olalde, Mishelle Paullus, Shailesh K Shahi, Kai Wang
• Ngôn ngữ: eng
• Ký hiệu phân loại: 616.834 *Multiple sclerosis
• Thông tin xuất bản: United States : Proceedings of the National Academy of Sciences of the United States of America , 2025
• Bộ sưu tập: NCBI
• ID: 692568

Tóm tắt

Gut microbiota dysbiosis is associated with multiple sclerosis (MS), but the causal relationship between specific gut bacteria and MS pathogenesis remains poorly understood. Therefore, we profiled the stool microbiome of people with MS (PwMS) and healthy controls (HC) using shotgun metagenomic sequencing. PwMS showed a distinct microbiome compared to HC, with