To advance biomedical engineering and enhance its therapeutic and diagnostic capabilities, the development of novel materials that can mimic the complexity of biological tissues is crucial. Hydrogels, with their high water content and biocompatibility, are particularly suitable for a wide range of medical applications. This research explores the synthesis and bioactivity of alginate hydrogels and their crosslinked derivatives within the biomedical field. We synthesized a series of alginate and p-phthaloyl crosslinked alginate films, which were further modified with imidazolium-based bi-ionic liquids and green-synthesized silver nanoparticles (AgNPs). The successful synthesis of these materials was confirmed using techniques such as FTIR, XRD, EDX, UV-Vis,