AIMS: The most used assessment tool to measure family-centered care and the perception of the care process is the Measure of Processes of Care questionnaire. This study aimed to evaluate the psychometric properties of the Spanish version of the MPOC-SP, specifically by assessing the reliability of its item scores, testing whether its factor structure aligns with the original version, and examining differences in scores across professional profiles. METHODS: The Spanish-adapted MPOC-SP questionnaire was completed by 278 early childhood service professionals across Spain. Analyses assessed internal consistency, construct validity through confirmatory factor analysis, and differences in scores across professional profiles. RESULTS: The Spanish MPOC-SP demonstrated strong psychometric properties, with Cronbach's Alpha values above 0.70 for total and dimensional scores. Confirmatory factor analysis supported the alignment of the data with the specified model. No significant differences in scores were found across professional profiles, indicating consistency in its application. CONCLUSION: The Spanish version of the MPOC-SP is a reliable and valid instrument for assessing family-centered care. It provides valuable insights for evaluating and improving family-centered practices in early childhood services, thereby contributing to the enhancement of care quality.