Electrochemical 3-Component Synthesis of Alkenesulfonates from Cinnamic Acids, SO2 and Alcohols.

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Tác giả: Florian A Breitschaft, Po-Chung Chien, Harald Kelm, Georg Manolikakes, Siegfried R Waldvogel

Ngôn ngữ: eng

Ký hiệu phân loại: 547.631 *Alcohols

Thông tin xuất bản: Germany : ChemSusChem , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 693864

A novel, electrochemical 3-component reaction for the synthesis of alkyl alkenesulfonates from cinnamic acids, SO2, and alkyl alcohols is reported. This metal-free process employs inexpensive and readily available graphite electrodes in combination with easy-to-use stock solutions of SO2 and enables a straightforward construction of the styrene sulfonate scaffold via a decarboxylative transformation. Mechanistic studies indicate a pseudo-Kolbe type reaction. This novel reaction pathway enables a regioselective synthesis of alkenesulfonates from substituted cinnamic acids without double bond translocation. Gram-scale and anolyte reusability experiments demonstrate the applicability of this process for the construction of alkenesulfonates from cinnamic acids as potential biogenic feedstock.
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