Exploring the Potential of Indole-3-acetic Acid Arylhydrazone Hybrids for Parkinson's Disease Treatment: A Comprehensive Evaluation of Neuroprotective, MAOB Inhibitory, and Antioxidant Properties.

• Tác giả: Neda Anastassova, Nadya Hristova-Avakumova, Magdalena Kondeva-Burdina, Miroslav Rangelov, Denitsa Stefanova, Nadezhda Todorova, Denitsa Yancheva
• Ngôn ngữ: eng
• Ký hiệu phân loại: 615.908 Treatment of poisoning
• Thông tin xuất bản: United States : ACS chemical neuroscience , 2025
• Bộ sưu tập: NCBI
• ID: 693893

Tóm tắt

In the current study, a small series of five indole-3-acetic acid-derived arylhydrazone hybrids were synthesized and subjected to comprehensive evaluation of their neuropharmacological and radical-scavenging properties. Minimal neurotoxic effects were observed across diverse subcellular fractions, with particular emphasis on the compound