TP53-Mutated Myeloid Neoplasms: 2024 Update on Diagnosis, Risk-Stratification, and Management.

• Tác giả: Daniel A Arber, Devendra K Hiwase, Mithun Vinod Shah
• Ngôn ngữ: eng
• Ký hiệu phân loại: 616.0757 Diseases
• Thông tin xuất bản: United States : American journal of hematology , 2025
• Bộ sưu tập: NCBI
• ID: 693989

Tóm tắt

Alterations in the tumor suppressor gene TP53 are common in human cancers and are associated with an aggressive nature. Approximately 8%-12% of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) harbor TP53 mutations (TP53