Rapid Detection of Aeromonas veronii Using GGDEF Gene-Based Colorimetric Loop-Mediated Isothermal Amplification.

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Tác giả: Kek Heng Chua, Tien Tien Vicky Lau, Suat Moi Puah

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: England : Journal of fish diseases , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 694120

Aeromonas veronii has emerged as an important fish pathogen that poses threats to the aquaculture industry worldwide, and rapid detection is essential to minimise negative economic impact. In this study, a colorimetric loop-mediated isothermal amplification (LAMP) assay was developed to rapidly detect A. veronii, targeting a gene encoding GGDEF domain-containing diguanylate cyclase. The entire LAMP reaction could be completed in 30 min at 65°C based on colour change from pink to yellow. In addition, the assay demonstrated 100% specificity with no cross reaction with other common fish pathogens. The detection limit (LOD) was 500 pg/μL using purified plasmid and 1.72 × 10
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