The aim of the study was to gain insight into the time course of whole-body electromyostimulation (WB-EMS)-induced inflammatory and endocrine factors over 72 h. Twelve healthy individuals (5 men, 7 women
33.0 ± 12 years) randomly performed a single 20-minute high-intensity WB-EMS and a time- and intensity-matched whole-body circuit training (CT) with a 3-week wash-out period. Blood samples were taken pre- and post-training and at 1.5, 3, 24, 48 and 72 h after exercise to assess creatine kinase (CK), myoglobin, and creatinine, cell populations (red and white blood cells [RBC, WBC], thrombocytes), cytokines (interleukin IL-1Ra, IL-6, IL-10, monocyte chemoattractant protein 1 [MCP-1]), angiogenic factors (IL-8, vascular endothelial growth factor [VEGF], thrombospondin), adipokines (leptin, adiponectin), and hormones (testosterone, cortisol). WB-EMS induced significant CK elevations peaking at 72 h (WB-EMS, 18,358 ± 21,380 vs. CT, 186 ± 129 U/l
time × group,