Regularly updated benchmark sets for statistically correct evaluations of AlphaFold applications.

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Tác giả: Laszlo Dobson, Peter Tompa, Gábor E Tusnády

Ngôn ngữ: eng

Ký hiệu phân loại: 910.468025 Accounts of travel and facilities for travelers

Thông tin xuất bản: England : Briefings in bioinformatics , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 694290

AlphaFold2 changed structural biology by providing high-quality structure predictions for all possible proteins. Since its inception, a plethora of applications were built on AlphaFold2, expediting discoveries in virtually all areas related to protein science. In many cases, however, optimism seems to have made scientists forget about data leakage, a serious issue that needs to be addressed when evaluating machine learning methods. Here we provide a rigorous benchmark set that can be used in a broad range of applications built around AlphaFold2/3.
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