Systematic Model Peptide Studies: A Crucial Step To Understand the Coordination Chemistry of Mn(II) and Fe(II) in Proteins.

• Tác giả: Elzbieta Gumienna-Kontecka, Malgorzata Ostrowska, Karolina Pawlik
• Ngôn ngữ: eng
• Ký hiệu phân loại: 945.084 Reigns of Victor Emmanuel II and Umberto I, 1861–1900
• Thông tin xuất bản: United States : Inorganic chemistry , 2025
• Bộ sưu tập: NCBI
• ID: 694336

Tóm tắt

Pathogenic bacteria and all other species require Mn(II) and Fe(II) ions for proper growth. Microbes use a variety of assimilation pathways to obtain the necessary metal ions, and their metal homeostasis mechanisms are still not fully uncovered. The knowledge of the poorly discovered complexation chemistry of Mn(II) and Fe(II) ions could help us to understand the basis of those processes better. We have designed six model peptides (L1 - Ac-HHHHHH-NH2, L2 - Ac-HHHHHHHHH-NH